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Anti-androgens for hair loss

This page is about use of androgen blockers to reduce hair loss. For readers seeking information on hormones as part of a gender transition, please visit this page.

A testosterone blocker can be helpful for reducing hair loss. These drugs are safe and effective, but the side effects may outweigh the hair loss benefits for some people, especially men who are not transgender.

Oral option:

  • Spironolactone   100 – 200 mg/day (up to 400 mg)
  • Cyproterone acetate   50–100 mg/day

Under the skin option:

  • GnRH agonists   3.75 mg subcutaneous monthly

Taking a prescription androgen blocker is the most effective way to address scalp hair loss.

  • Finasteride (Proscar and Propecia)
  • Dutasteride (Avodart)
  • Cyproterone acetate (Androcur)
  • Spironolactone (Aldactone)
  • Hydroxyprogesterone caproate (Proluton, Proluton Depot)
  • Medroxyprogesterone acetate (Depo-Provera)